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6 Common American Shorthair Cat Health Problems

March 2, 2021 by The Spot Pack
Gray American Shorthair Cat

You can recognize the beautiful American Shorthair Cat immediately with its array of colors and patterns, especially when you see the silver tabby, one of the most popular American Shorthair Cat colorings.

Your good-natured feline may fit right in with your family and even get along great with your kids. Though your American Shorthair cat loves attention (and might occasionally even get along with your next-door neighbor’s super-friendly dog), this diverse breed might encounter a few health problems.

It’s a good idea to learn more about the breed if you think you might add American Shorthair Cat to your family — including American Shorthair health risks.

Common American Shorthair Cat Health Risks

Heart Disease

Your American Shorthair Cat may suffer from heart muscle disease through an inherited condition through other diseases that damage the heart.

●      Hypertrophic cardiomyopathy (HCM) refers to the thickening of the heart muscle and often occurs due to an overactive thyroid gland.

●      Dilated cardiomyopathy (DCM) results due to a deficiency of the amino acid taurine, found in food. (Most cat food brands add taurine to foods today.)

Check for rapid breathing, lethargy, and a poor appetite to signal heart disease. To get a specific diagnosis, your veterinarian must use advanced medical imaging on your American Shorthair Cat. Have your pet evaluated twice a year for heart problems.

Feline Lower Urinary Tract Diseases

Urinating outside the litter box may signal improper nerve function from a spinal defect, called Feline Lower Urinary Tract Diseases (FLUTD).

Any signs of urination outside the litter box (such as on cool surfaces), blood in the urine, little urine production when trying to urinate or crying in the litterbox can indicate FLUTD. Your American Shorthair’s inability to urinate can quickly become fatal, so get your cat to your veterinarian as soon as possible.
At every checkup, your veterinarian should always check for signs of kidney disease, infection, urine crystals and diabetes, and if needed, through X-rays and ultrasounds. Severe FLUTD cases may require surgery.

Renal Failure

American Shorthair Cats may suffer from renal failure, which means their kidneys don’t properly cleanse waste from the blood and regulate hydration. Kidney disease happens often in older cats but can happen in younger cats as well. Make sure your veterinarian screens for kidney problems early and regularly. Severe renal failure can turn fatal, but special diets and medications can help your American Shorthair Cat if caught early.


Many middle-aged American Shorthair Cats develop a benign (non-cancerous) tumor in the thyroid gland, causing hyperthyroidism. This causes a lack of control of the hormone called T4 from the thyroid gland — the thyroid pumps out T4 despite signals to stop.

Watch for vomiting, weight loss, and increased thirst because hyperthyroidism can lead to heart failure, kidney failure, and fatal blood clots.

Make sure your vet looks for hyperthyroidism using a blood test during checkups. Treatment can cure the disease and help your American Shorthair Cat lead a normal life.

Diabetes Mellitus

Your American Shorthair has a genetic predisposition to diabetes mellitus, a genetic disease that can occur in any cat breed. Diabetes most often occurs if you allow your cat to become overweight or eat a poor diet.

If you have an indoor cat, keep your American Shorthair active to prevent weight gain. How much should a domestic shorthair cat weigh? The average domestic shorthair cat should weigh 8 to 10 pounds (3.6 to 4.5 kg), though some individual variation in American Shorthair Cats may occur. [1]

Diabetes can result in pancreatitis, a disease that leads to damage of the cells in the pancreas that produce insulin.

Look for weight loss despite a healthy appetite, excessive thirst and frequent urination. Ask your vet to test your cat as part of your cat’s annual wellness exams. Cats may need regular insulin injections if they lose weight as well as a high-protein, low-carb diet.

Polycystic Kidney Disease

Defective genes cause polycystic kidney disease (PKD) and American Shorthair Cats are prone to the disease. Miniscule cysts develop inside the kidneys and the liver, which slowly enlarge over time and destroy the affected organ(s).

Look for weight loss, thirst, vomiting and poor overall health.

Special diets and medication can slow the progress of end-stage organ failure but there is no cure for PKD. Urine or blood testing can detect organ dysfunction in your American Shorthair Cat. You can have your cat undergo genetic testing for PKD.

How Long Do Domestic Shorthair Cats Live?

Domestic Shorthair Cats who live indoors can live 13 to 17 years on average. Some live much shorter lives, while others live well into their 20s. Outdoor cats only live two to five years on average, due to the dangers that these cats face, including predators and traffic.[2]

Pet Insurance for American Shorthair Cats

Your American Shorthair Cat is an important member of your family. You want to give your beloved feline the right veterinary care so your furry friend can live as healthy as possible!

Sign up for a pet insurance policy today while you have a young American Shorthair Cat. Doing so sets you up to be reimbursed later on in life if your cat develops a chronic illness or other covered condition.

Let Spot Pet Insurance help you with the costs of giving your cat the best life possible.


Melissa Brock, pet parent of a black fur-shedding feline, is the founder of College Money Tips and Money editor at Benzinga. She loves helping families navigate their finances.

Sources: Vet Street, The Vet on Fourth

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